Ethyl 4-acetoxy-4-chloro-2-hydroxy-2-methylbutanoate CAS 80350-42-1

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 4-acetoxy-4-chloro-2-hydroxy-2-methylbutanoate.

Ethyl 4-acetoxy-4-chloro-2-hydroxy-2-methylbutanoate (CAS 80350-42-1), molecular formula C9H15ClO5 and molecular weight 238.67 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Ethyl 4-acetoxy-4-chloro-2-hydroxy-2-methylbutanoate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 238.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Ethyl 4-acetoxy-4-chloro-2-hydroxy-2-methylbutanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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