N,N-Dibutyl-2-(diphenylphosphoryl)acetamide CAS 80413-41-8

Purity 97%+In StockPharmaceutical Standards
CAS No.80413-41-8
Molecular FormulaC22H30NO2P
Molecular Weight371.45 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N,N-Dibutyl-2-(diphenylphosphoryl)acetamide CAS 80413-41-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N,N-Dibutyl-2-(diphenylphosphoryl)acetamide.

N,N-Dibutyl-2-(diphenylphosphoryl)acetamide (CAS 80413-41-8), molecular formula C22H30NO2P and molecular weight 371.45 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of N,N-Dibutyl-2-(diphenylphosphoryl)acetamide (C22H30NO2P) is characterized by a steroid core, an amide group, organophosphorus functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures N,N-Dibutyl-2-(diphenylphosphoryl)acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC22H30NO2P
Molecular Weight371.45 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1979
Nitrogen Atoms1

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