Mafoprazine CAS 80428-29-1
| CAS No. | 80428-29-1 |
| Molecular Formula | C22H28FN3O3 |
| Molecular Weight | 401.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Mafoprazine.
Mafoprazine (CAS 80428-29-1) is a high-purity analytical reference standard with the molecular formula C22H28FN3O3 and a molecular weight of 401.47 g/mol.
Structurally, Mafoprazine (C22H28FN3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 401.47 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Mafoprazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H28FN3O3 |
| Molecular Weight | 401.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
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- Fmoc-β-Homo-Phe-OH (CAS 193954-28-8)
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- OICR-9429 (CAS 1801787-56-3)
- 2-(Aminooxy)-2-methylpropanoic acid hydrochloride (CAS 89766-91-6)
- Methyl 4-(((trifluoromethyl)sulfonyl)oxy)-2H-thiochromene-7-carboxylate (CAS 2768536-02-1)
- Thymopoietin II Peptide Fragment (CAS 56795-64-3)
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