Calcium levofolinate CAS 80433-71-2
| CAS No. | 80433-71-2 |
| Molecular Formula | C20H21N7O7 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Calcium levofolinate is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Calcium levofolinate (CAS 80433-71-2), molecular formula C20H21N7O7Ca and molecular weight 511.51 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C20H21N7O7Ca, Calcium levofolinate contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 511.51 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Calcium levofolinate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H21N7O7 Ca |
| Molecular Weight | 511.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 7 |
Related Calcium Standards
- Calcium Levofolinate EP Impurity I Calcium salt (CAS 1148151-21-6)
- Calcium Levofolinate Pentahydrate - Impurity G (Dihydrate Salt) (CAS 207226-40-2)
- Calcium Levofolinate EP Impurity F(Calcium salt) (CAS 28459-40-7(free base))
- Calcium Levofolinate EP Impurity I (CAS 31690-11-6)
- Levofolinate Impurity 8 (CAS 4299-32-5)
- Calcium Levofolinate EP Impurity H (CAS 73951-54-9)
- Levofolinate EP Impurity H Calcium salt (CAS 73951-54-9（Free base）)
- Calcium Levofolinate EP Impurity E Calcium salt (CAS 944737-05-7（free base）)
Recommended Standards
- 2-(1-Cyclopentylpiperidin-4-yl)ethanamine (CAS 132740-61-5)
- 4-Butyl-N-(2-(4-nitrophenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl)cyclohexane-1-carboxamide (CAS 396724-07-5)
- N-(4-Bromo-2-fluorophenyl)benzenesulfonamide (CAS 519017-71-1)
- (Methylenebis(2-hydroxy-4-methoxy-5,1-phenylene))bis(phenylmethanone) (CAS 68716-15-4)
- Dequalinium EP Impurity C trichloride (CAS 171980-50-0)
- (4-Fluorophenyl)(5-(pyrazin-2-yl)-1H-1,2,4-triazol-3-yl)methanamine (CAS 1707585-71-4)
- 2-((4-Chlorophenyl)amino)-2-phenylacetonitrile (CAS 4686-05-9)
- Benzyl (2-bromo-6-iodophenyl)carbamate (CAS 1427501-71-0)
- Venetoclax Impurity 109 (CAS CATO-C4X-2495109)
- ([13C6]Leu14)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt (CAS 1802078-39-2)
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