1-Benzyl-1,2,3,6-tetrahydropyridine hydrochloride CAS 80477-52-7
| CAS No. | 80477-52-7 |
| Molecular Formula | C12H15N |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-Benzyl-1,2,3,6-tetrahydropyridine hydrochloride is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-Benzyl-1,2,3,6-tetrahydropyridine hydrochloride (CAS 80477-52-7), molecular formula C12H15NHCl and molecular weight 209.72 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Benzyl-1,2,3,6-tetrahydropyridine hydrochloride (C12H15NHCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-Benzyl-1,2,3,6-tetrahydropyridine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15N HCl |
| Molecular Weight | 209.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Benzyl Standards
- 4-Phenyl-1,2,3,6-tetrahydropyridine (CAS 10338-69-9)
- 1-Benzyl-1,2,3,6-tetrahydropyridine-4-D (CAS 1036203-25-4)
- 1-Benzyl-1,2,3,6-tetrahydropyridine-4-boronic Acid Pinacol Ester (CAS 1048976-83-5)
- Methyl 3,4,5,6-tetrahydropyridine-2-carboxylate (CAS 108602-80-8)
- Methyl 1,4,5,6-tetrahydropyridine-2-carboxylate (CAS 108602-82-0)
- 3-(4-(4-Phenyl-1,2,3,6-tetrahydropyridine-1-carbonyl)piperidin-1-yl)quinoxalin-2(1H)-one (CAS 1206984-71-5)
- 1-Methyl-1,2,5,6-tetrahydropyridine-3-boronic Acid Pinacol Ester (CAS 1254982-25-6)
- 2-Acetyl-3,4,5,6-tetrahydropyridine-13C2 Hydrochloride(Technical Grade) (CAS 1346604-15-6)
Recommended Standards
- (E)-tert-Butyl 3-((dimethylamino)methylene)-4-oxopyrrolidine-1-carboxylate (CAS 1819364-04-9)
- 3'-Isopropoxy-[1,1'-biphenyl]-4-thiol (CAS 1443352-72-4)
- Ethyl 2-amino-4-isopropylthiophene-3-carboxylate (CAS 72965-16-3)
- 4-Mercaptobenzo[d]oxazole-2-carbonitrile (CAS 1806339-64-9)
- tert-butyl N-[(3R,4R)-3-aminotetrahydropyran-4-yl]carbamate (CAS 1340474-87-4)
- 3-(4-Isobutoxy-1,2,5-thiadiazol-3-yl)aniline (CAS 1365938-99-3)
- Diaveridine-d6 (CAS CATO-CCPD103223)
- 1-Isobutyrylindoline-5-carboxylic acid (CAS 1051188-71-6)
- 1-Ethyl-N-(2-phenoxyphenyl)-1H-benzo[d][1,2,3]triazole-5-carboxamide (CAS 854039-48-8)
- Semaglutide impurity 26 (CAS CATO-C4X-222626)
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