4-(2-Phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl)phenol CAS 805239-56-9
| CAS No. | 805239-56-9 |
| Molecular Formula | C20H11F6N3O |
| Molecular Weight | 423.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 4-(2-Phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl)phenol (CAS 805239-56-9), a certified reference material (molecular formula C20H11F6N3O, MW 423.31 g/mol) for analytical method development and quality control.
The molecular framework of 4-(2-Phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl)phenol (C20H11F6N3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H11F6N3O |
| Molecular Weight | 423.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- 2-{[(2,6-dichlorophenyl)methyl]sulfanyl}-5-methoxy-4-(4-methoxyphenoxy)pyrimidine (CAS 338956-00-6)
- 4-[(4-Chlorobenzenesulfonyl)methyl]-6-[(2-chlorophenyl)methoxy]-2-methylpyrimidine (CAS 338960-44-4)
- 2-{[(2,4-dichlorophenyl)methyl]sulfanyl}-5-methoxy-4-(4-methoxyphenoxy)pyrimidine (CAS 339275-92-2)
- N-(1-(3,4-dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)-4-methylbenzenesulfonamide (CAS 400086-24-0)
- 2-(2-(Aminomethyl)-1H-pyrrol-1-yl)acetic acid (CAS 145041-27-6)
- Ethyl 5-oxo-1,2,3,5-tetrahydroimidazo[1,2-a]pyridine-8-carboxylate (CAS 439118-88-4)
- 1H-indole, 5-ethoxy-2,3-dihydro-3,3-dimethyl (CAS 87234-81-9)
- Methyl 2-((tert-butoxycarbonyl)amino)butanoate (CAS 58561-08-3)
- 2-(4-Methoxybenzoyl)benzoic acid (CAS 1151-15-1)
- N-(Undec-10-en-1-yl)pent-4-ynamide (CAS 920279-10-3)
- 3-(4-Chlorophenyl)pyridine (CAS 5957-97-1)
- 6-(Chloromethyl)-2-n-(4-fluorophenyl)-1,3,5-triazine-2,4-diamine (CAS 105704-32-3)
- 5-amino-2-benzyl-1,3-oxazole-4-carbonitrile (CAS 887748-74-5)
- Semaglutide impurity 39 (CAS CATO-C4X-222639)
Why CATO?
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