6-beta Hydroxy Fludrocortisone CAS 806-36-0
| CAS No. | 806-36-0 |
| Molecular Formula | C21H29FO6 |
| Molecular Weight | 396.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-beta Hydroxy Fludrocortisone is closely related to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-beta Hydroxy Fludrocortisone (CAS 806-36-0) is a high-purity analytical reference standard with the molecular formula C21H29FO6 and a molecular weight of 396.45 g/mol.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution, 6-beta Hydroxy Fludrocortisone is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 396.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H29FO6 |
| Molecular Weight | 396.45 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
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Recommended Standards
- 2-Mercapto-3-(2-(trifluoromethyl)phenyl)-3,5,6,7,8,9-hexahydro-4h-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-one (CAS 565195-77-9)
- Cyclopropyl[4-(1-{[6-(trifluoromethyl)-3-pyridinyl]methyl}-4-piperidinyl)-1-piperazinyl]methanone (CAS 909670-30-0)
- 2-(4-{3-fluoro-4'-[(1-hydroxypropan-2-yl)oxy]-[1,1'-biphenyl]-4-yl}phenoxy)propan-1-ol (CAS 477860-07-4)
- Triamcinolone EP Impurity C (CAS 337-02-0)
- 1-[(3,4-Dimethoxyphenyl)methyl]-4-hydroxy-3-[(2E)-3-phenylprop-2-en-1-yl]-1,2-dihydropyridin-2-one (CAS 477888-18-9)
- 4-(Dimethylamino)-N-isobutylbenzamide (CAS 851613-30-4)
- 6-Amino-5-formyl-2-(methyl(prop-2-yn-1-yl)amino)nicotinonitrile (CAS 1335032-61-5)
- 2-Bromo-1-(3-chloropropyl)-4-fluorobenzene (CAS 1057673-31-0)
- 4-Hydroxy-1-isopropylpiperidine (CAS 5570-78-5)
- Nedaplatin Impurity C183 (CAS 20115-65-5)
- 2-(4-bromo-2-methylphenyl)propan-2-ol (CAS 877132-71-3)
- 5-Bromo-1H-indazol-6-amine (CAS 1360900-38-4)
- 2-(2,5-Difluorophenyl)-1h-1,3-benzodiazol-5-amine (CAS 1016688-16-6)
- Semaglutide Impurity 149 (CAS CATO-C4X-2226149)
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