Ceftriaxone EP Impurity D CAS 80756-85-0
| CAS No. | 80756-85-0 |
| Molecular Formula | C13H10N4O2S3 |
| Molecular Weight | 350.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Ceftriaxone EP Impurity D (CAS 80756-85-0, C13H10N4O2S3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Ceftriaxone EP Impurity D is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 350.44 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ceftriaxone EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H10N4O2S3 |
| Molecular Weight | 350.44 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 3 |
Related Ceftriaxone Standards
- Ceftriaxone Impurity 4 (CAS 959246-33-4)
- Ceftriaxone Impurity 31 (CAS CATO-C4X-116331)
- Ceftriaxone Impurity 46 (CAS CATO-C4X-116346)
- Ceftriaxone EP Impurity E (CAS 58909-56-1)
- Ceftriaxone Impurity 43 (CAS CATO-C4X-116343)
- Ceftriaxone Impurity 47 (CAS CATO-C4X-116347)
- Ceftriaxone Impurity 9 (CAS CATO-C4X-11639)
- Ceftriaxone Sodium EP Impurity B(Cefotaxime EP Impurity E)（Cefodizime Impurity D） (CAS 66340-33-8)
Recommended Standards
- Ilaprazole Impurity 70 (CAS 2285346-40-7)
- Isavuconazole Impurity 196 (CAS CATO-C4X-1236196)
- Ilaprazole Impurity 17 (CAS 172152-35-1)
- Isavuconazole Impurity 197 (CAS CATO-C4X-1236197)
- Salcaprozate Impurity 15 (CAS 2780975-72-4)
- Levocabastine EP Impurity E (CAS CATO-C4X-22895)
- Ramelteon Impurity 60 (CAS CATO-C4X-262260)
- 6-Methoxy-2-methyl-1,3-benzoxazole (CAS 23999-64-6)
- 2-(3,5-Dichloro-4-hydroxyphenethyl)isoindoline-1,3-dione (CAS 889651-04-1)
- 4-Chloro-5-(difluoromethyl)-3-(trifluoromethyl)picolinonitrile (CAS 1806868-75-6)
- methyl 3-fluoro-5-hydroxypyridine-2-carboxylate (CAS 1256836-96-0)
- Ethyl 4-(4-chlorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate (CAS 329700-15-4)
- Ethyl 6,7-dihydro-5H-cyclopenta[c]pyridine-6-carboxylate (CAS 607345-41-5)
- Tau Peptide (273-284) trifluoroacetate salt (CAS 1663490-91-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com