2-Deoxyguanosine-5-O-(1-thiotriphosphate) CAS 80902-28-9
| CAS No. | 80902-28-9 |
| Molecular Formula | C10H16N5O12P3S |
| Molecular Weight | 523.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Deoxyguanosine-5-O-(1-thiotriphosphate) (CAS 80902-28-9), molecular formula C10H16N5O12P3S and molecular weight 523.25 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-Deoxyguanosine-5-O-(1-thiotriphosphate) (C10H16N5O12P3S) contains a carbohydrate-derived structure, an amide group, a sulfone group, a phosphate ester group. The molecule exhibits a degree of unsaturation (DBE) of 5.5, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 523.25 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 2-Deoxyguanosine-5-O-(1-thiotriphosphate) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H16N5O12P3S |
| Molecular Weight | 523.25 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Deoxyguanosine Standards
- 2'-Deoxyguanosine-5'-O-(α-thio)triphosphate (CAS 82337-56-2)
- 8-Oxo-2-deoxyguanosine 5-Triphosphate (CAS 139307-94-1)
- 2-Deoxyguanosine 3,5-Dibutanoate (CAS 79971-08-7)
- 2'-Deoxyguanosine-5'-monophosphate (CAS 902-04-5)
- 7-Ethyl-2-deoxyguanosine (CAS 50704-45-5)
- 8-Oxo-2’-deoxyguanosine-13C,15N2 (CAS CATO-CCHM704003)
- 3-Deoxyguanosine (CAS 3608-58-0)
- α-2’-Deoxyguanosine (CAS 19916-78-0)
Recommended Standards
- 2-({5-chloro-1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-oxo-1,6-dihydropyridazin-4-yl}(methyl)amino)ethyl 2,6-difluorobenzoate (CAS 338400-01-4)
- 2-((4-Allyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,6-dibromo-4-methylphenyl)acetamide (CAS 585560-04-9)
- Adenosine 5′-(3-thiotriphosphate) (CAS 35094-46-3)
- 3-Chloro-2-[(1E)-(4-chlorophenyl)({2-[2-nitro-4-(trifluoromethyl)phenyl]hydrazin-1-ylidene})methyl]-5-(trifluoromethyl)pyridine (CAS 338770-77-7)
- 2-Amino-3-(4-fluoro-2-methylphenyl)-3-hydroxypropanoic acid (CAS 1497949-89-9)
- 4-(Benzylamino)tetrahydro-2H-pyran-4-carboxamide (CAS 1178742-81-8)
- Upadacitinib (CAS 1310726-60-3)
- 3-(2-Hydroxy-1-Methyl-2-Nitrosohydrazino)-N-Methyl-1-Propanamine (CAS 146724-84-7)
- 8-Methoxyphenanthro[3,4-d][1,3]dioxole-5-carboxylic acid (CAS 35142-05-3)
- Dinitrodenafil, 98% (CAS 1797103-21-9)
- 3-Chloroisoquinoline-4-carbaldehyde (CAS 120285-29-2)
- 2,3,4,5,6,6-Hexachlorocyclohexa-2,4-dienone (CAS 21306-21-8)
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