(3R,4S)-1-Benzyl-4-(4-fluorophenyl)pyrrolidine-3-carboxylicacid CAS 80909-49-5
| CAS No. | 80909-49-5 |
| Molecular Formula | C18H18FNO2 |
| Molecular Weight | 299.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(3R,4S)-1-Benzyl-4-(4-fluorophenyl)pyrrolidine-3-carboxylicacid (CAS 80909-49-5) is a high-purity analytical reference standard with the molecular formula C18H18FNO2 and a molecular weight of 299.34 g/mol.
(3R,4S)-1-Benzyl-4-(4-fluorophenyl)pyrrolidine-3-carboxylicacid (C18H18FNO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (3R,4S)-1-Benzyl-4-(4-fluorophenyl)pyrrolidine-3-carboxylicacid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H18FNO2 |
| Molecular Weight | 299.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (2-Fluorophenyl)(4-(morpholinomethyl)phenyl)methanone (CAS 898770-32-6)
- (4-Aminophenyl)(4-(2-fluorophenyl)piperazin-1-yl)methanone (CAS 885949-71-3)
- (2-Fluorophenyl)(3-(morpholinomethyl)phenyl)methanone (CAS 898791-92-9)
- (4E)-4-(1,3-benzothiazol-2-yl)-5-(2-furyl)pent-4-enoic acid (CAS 852851-67-3)
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- N-(4-(2,5-Dimethylphenyl)thiazol-2-yl)isoxazole-5-carboxamide (CAS 919759-02-7)
- Methyl 3-((4-bromo-2-chlorophenoxy)methyl)benzoate (CAS 832737-25-4)
- Ethyl 2-Amino-2-phenylacetate Hydrochloride (CAS 879-48-1)
- Bis(3,4-dimethylphenyl)iodonium hexafluorophosphate (CAS 67578-25-0)
- n-Propylpyrrolidine-2-carboxamide (CAS 1160708-87-1)
- 4-(2-Chlorophenyl)-2-(3-chlorophenyl)-1,2-dihydro-3H-pyrazol-3-one (CAS 400076-68-8)
- 3-((4-Fluorophenyl)thio)-6-phenylpyridazine-4-carbonitrile (CAS 338417-93-9)
- Semaglutide impurity 270 (CAS CATO-C4X-2226270)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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