Ethyl 1-(4-fluorophenyl)-4-oxocyclohexane-1-carboxylate CAS 80912-59-0

Purity 97%+In StockPharmaceutical Standards
CAS No.80912-59-0
Molecular FormulaC15H17FO3
Molecular Weight264.29 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 1-(4-fluorophenyl)-4-oxocyclohexane-1-carboxylate CAS 80912-59-0 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 1-(4-fluorophenyl)-4-oxocyclohexane-1-carboxylate.

CATO supplies Ethyl 1-(4-fluorophenyl)-4-oxocyclohexane-1-carboxylate (CAS 80912-59-0), a certified reference material (molecular formula C15H17FO3, MW 264.29 g/mol) for analytical method development and quality control.

The molecular framework of Ethyl 1-(4-fluorophenyl)-4-oxocyclohexane-1-carboxylate (C15H17FO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Ethyl 1-(4-fluorophenyl)-4-oxocyclohexane-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC15H17FO3
Molecular Weight264.29 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1980
Halogen ContentF-containing

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