Albendazole EP Impurity F CAS 80983-45-5
| CAS No. | 80983-45-5 |
| Molecular Formula | C10H11N3O2S |
| Molecular Weight | 237.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Albendazole EP Impurity F (CAS 80983-45-5) is a certified pharmaceutical impurity reference standard with the molecular formula C10H11N3O2S and a molecular weight of 237.28 g/mol.
The molecular framework of Albendazole EP Impurity F (C10H11N3O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11N3O2S |
| Molecular Weight | 237.28 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Albendazole Standards
- Albendazole EP Impurity D (CAS 80983-34-2)
- Albendazole impurity 32 (CAS CATO-C4X-153532)
- Albendazole impurity 37 (CAS CATO-C4X-153537)
- Albendazole Impurity 39 (CAS 56694-07-6)
- Albendazole EP Impurity G (CAS 20367-38-8)
- Albendazole Impurity N5 (CAS 50-97-5)
- Albendazole impurity 33 (CAS CATO-C4X-153533)
- Albendazole impurity 35 (CAS CATO-C4X-153535)
Recommended Standards
- 338393-13-8 5-[(4-Methylphenyl)methanesulfonyl]-1H-1,2,4-triazole DTXSID40366374 (CAS 338393-13-8)
- 3-(Isobutylcarbamoyl)bicyclo[2.2.1]Hept-5-ene-2-carboxylic acid (CAS 1005263-01-3)
- 2-Amino-benzothiazole-6-carboxylic acid (2-hydroxy-ethyl)-amide 2-amino-benzothiazole-6-carboxylic acid(2-hydroxy-ethyl)-amide 2-amino-n-(2-hydroxyethyl)-1,3-benzothiazole-6-carboxamide 313504-87-9 (CAS 313504-87-9)
- 3-{4-[2-(dimethylamino)ethoxy]phenyl}propanoic acid (CAS 100619-09-8)
- Adenosine Impurity 28 (CAS 162660-35-7)
- Ciprofibrate EP Impurity B (CAS 52179-26-7)
- Ozenoxacin Impurity 58 (CAS CATO-C4X-279658)
- 1-(oxan-4-yl)guanidine hydrochloride (CAS 1447606-48-5)
- 1-(Cyclopropylmethyl)-1H-pyrazole-3-carbaldehyde (CAS 1352520-09-2)
- Tert-butyl (3S,4S)-3-((2-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)-4-fluoropiperidine-1-carboxylate (CAS 2227198-12-9)
- (4R)-5,8-difluoro-3,4-dihydro-2H-1-benzopyran-4-amine hydrochloride (CAS 1807938-54-0)
- (R)-1-(3-Ethoxyphenyl)ethanamine hydrochloride (CAS 1213097-29-0)
- 2-Hydroxyethyl n-(4-sulfamoylphenyl)carbamate (CAS 121-64-2)
- FMRF Amide Related Peptide. (CAS 149471-12-5)
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