2-Chloro-1,4-dihydroxyanthracene-9,10-dione CAS 81-53-8
| CAS No. | 81-53-8 |
| Molecular Formula | C14H7ClO4 |
| Molecular Weight | 274.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Chloro-1,4-dihydroxyanthracene-9,10-dione (C14H7ClO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 2-Chloro-1,4-dihydroxyanthracene-9,10-dione (CAS 81-53-8), a certified reference material (molecular formula C14H7ClO4, MW 274.66 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Chloro-1,4-dihydroxyanthracene-9,10-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H7ClO4 |
| Molecular Weight | 274.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Chloro Standards
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Recommended Standards
- 2-(4-Chlorophenyl)-5-nitrobenzo[d]oxazole (CAS 962-25-4)
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- 3-(5-Chloropyridin-3-yl)-5-nitro-1H-indazole (CAS 1356088-13-5)
- 4-Chloro-3-cyano-N-(6-oxo-1,6-dihydropyrimidin-5-yl)benzamide (CAS 918880-71-4)
- 9,10-Dihydroanthracen-9-amine (CAS 97825-91-7)
- 2-(2-cyclohexylethyl)pyrrolidine (CAS 383127-76-2)
- 3-Chloro-2-(pyrrolidin-1-yl)aniline (CAS 58785-05-0)
- (R)-1-(3-fluoro-4-(trifluoromethoxy)phenyl)pentan-1-amine (CAS 1272732-83-8)
- Cicloprolol (CAS 94651-09-9)
- 2-Bromo-N-((2-(2,3-dimethylphenyl)benzo[d]oxazol-5-yl)carbamothioyl)benzamide (CAS 590396-68-2)
- 2-Propenoic acid, polymer with N-(butoxymethyl)-2-propenamide, ethenylbenzene and ethyl 2-propenoate (CAS 51749-41-8)
- 6-((Tert-butoxycarbonyl)(methyl)amino)nicotinic acid (CAS 365413-11-2)
- 2-(Aminomethyl)-6-chloro-4-(difluoromethyl)-3-methoxypyridine (CAS 1805412-95-6)
- Serpent Peptide (CAS 823202-99-9)
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