S-Adenosyl-L-Methionine Impurity 11 CAS 81012-86-4
| CAS No. | 81012-86-4 |
| Molecular Formula | C10H14N5O7P |
| Molecular Weight | 347.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
S-Adenosyl-L-Methionine Impurity 11 (CAS 81012-86-4) is a certified pharmaceutical impurity reference standard with the molecular formula C10H14N5O7P and a molecular weight of 347.22 g/mol.
S-Adenosyl-L-Methionine Impurity 11 (C10H14N5O7P) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H14N5O7P |
| Molecular Weight | 347.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Nitrogen Atoms | 5 |
Related S Standards
- S-Adenosyl-L-Methionine Impurity 12 (CAS 84-21-9)
- S-(5')-Adenosyl-3-thiopropylamine (CAS 53186-57-5)
- S-Adenosyl-L-Methionine Impurity 28 (CAS CATO-C4X-138128)
- S-Adenosyl-L-Methionine Impurity 10 (CAS 4229-50-9)
- S-Adenosyl-L-Methionine Impurity 19 (CAS 13484-65-6)
- Adenosyl Methionine Impurity 8 (CAS 59987-48-3)
- S-(5'-Adenosyl)-L-homocysteine (CAS 979-92-0)
- S-Adenosyl-L-Methionine Impurity 27 (CAS 911667-93-1)
Recommended Standards
- Poly(A) (CAS 24937-83-5)
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- N-(3,4-Dichlorophenyl)-2-(2-methyl-3,5-dioxothiomorpholino)acetamide (CAS 868215-99-0)
- Lemborexant Impurity 56 (CAS CATO-C4X-304256)
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- Argatroban Impurity 67 (CAS CATO-C4X-100767)
- 4-(3-Hydroxypropoxy)benzonitrile (CAS 147749-97-1)
- (4-Aminopiperidin-1-yl)(3-methoxyphenyl)methanone hydrochloride (CAS 1158290-89-1)
- Nifedipine Impurity 18 (CAS CATO-C4X-141018)
- Peptide T (CAS 106362-32-7)
- 1-Benzyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-sulfonyl chloride (CAS 1334145-97-9)
- 3-Aza-bicyclo[4.1.0]heptane (CAS 286-09-9)
- Tirzepatide Impurity 52 (CAS CATO-C4X-324052)
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