2-Thioxo-3-(3-(trifluoromethyl)phenyl)-2,3-dihydroquinazolin-4(1h)-one CAS 81066-86-6
| CAS No. | 81066-86-6 |
| Molecular Formula | C15H9F3N2OS |
| Molecular Weight | 322.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Thioxo-3-(3-(trifluoromethyl)phenyl)-2,3-dihydroquinazolin-4(1h)-one (C15H9F3N2OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 2-Thioxo-3-(3-(trifluoromethyl)phenyl)-2,3-dihydroquinazolin-4(1h)-one (CAS 81066-86-6), a certified reference material (molecular formula C15H9F3N2OS, MW 322.30 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Thioxo-3-(3-(trifluoromethyl)phenyl)-2,3-dihydroquinazolin-4(1h)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H9F3N2OS |
| Molecular Weight | 322.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Thioxo Standards
- N-(3-thioxo-3H-1,2,4-dithiazol-5-yl)-3-(trifluoromethyl)benzamide (CAS 306980-51-8)
- 2-(2-((5-Thioxo-4,5-dihydro-1,3,4-thiadiazol-2-yl)thio)ethyl)isoindoline-1,3-dione (CAS 477846-18-7)
- Methyl 4-(2-thioxo-5-(trifluoromethyl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)butanoate (CAS 400736-31-4)
- 2-(4-Oxo-2-thioxo-1,4-dihydroquinazolin-3(2H)-yl)-N-(pyridin-3-ylmethyl)acetamide (CAS 451465-83-1)
- 4-(5-Oxo-2-thioxo-3,4,4-trimethyl-1-imidazolidinyl)-2-trifluoromethylbenzonitrile (CAS 143782-25-6)
- 4-((4-Phenyl-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methoxy)benzoic acid (CAS 937605-30-6)
- 3-Thioxo-2-(3-(trifluoromethyl)phenyl)hexahydroimidazo[1,5-a]pyridin-1(5H)-one (CAS 60725-93-1)
- 4-(4-Oxo-2-thioxo-1,2-dihydroquinazolin-3(4H)-yl)benzenesulfonic acid (CAS 34330-07-9)
Recommended Standards
- 2-Sulfanyl-3-[2-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-one (CAS 727704-63-4)
- 3-Phenyl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxamide (CAS 478260-63-8)
- 2-{[2-cyano-2-phenyl-1-(trifluoromethyl)vinyl]thio}pyridinium-1-olate (CAS 256529-49-4)
- 4-((3-(Trifluoromethyl)phenyl)sulfonyl)piperazine-1-carbaldehyde (CAS 866152-66-1)
- 2-((5-Chloropyridin-3-yl)oxy)ethane-1-sulfonyl chloride (CAS 1342581-64-9)
- 5-Amino-1-(1-methyl-1H-pyrazol-4-yl)piperidin-2-one 2,2,2-trifluoroacetate (CAS 2137994-21-7)
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(((benzyloxy)carbonyl)amino)butanoic acid (CAS 387824-79-5)
- 6-Methylmorpholine-2-carboxylic acid hydrochloride (CAS 2137815-85-9)
- (2-(Isopentylthio)-1-(4-methylbenzyl)-1H-imidazol-5-yl)methanol (CAS 941891-49-2)
- 6-Bromopyrido[2,3-b]pyrazine (CAS 1204298-53-2)
- 1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole-7-carboxylic Acid (CAS 1268335-28-9)
- Erbium(III) perchlorate, 50% aqueous solution (99.9%-Er) (REO) (CAS 61565-07-9)
- Methyl 2-((4-cyano-1-ethyl-5,6,7,8-tetrahydroisoquinolin-3-yl)thio)acetate (CAS 1411990-76-5)
- Palmitoyl hexapeptide-6 (CAS 891498-01-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com