n-(Adamantan-1-ylmethyl)-2-chloroacetamide CAS 81099-48-1
| CAS No. | 81099-48-1 |
| Molecular Formula | C13H20ClNO |
| Molecular Weight | 241.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including n-(Adamantan-1-ylmethyl)-2-chloroacetamide.
CATO supplies n-(Adamantan-1-ylmethyl)-2-chloroacetamide (CAS 81099-48-1), a certified reference material (molecular formula C13H20ClNO, MW 241.76 g/mol) for analytical method development and quality control.
The molecular framework of n-(Adamantan-1-ylmethyl)-2-chloroacetamide (C13H20ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H20ClNO |
| Molecular Weight | 241.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related n Standards
- n-(Adamantan-1-yl)-2-chloropropanamide (CAS 90477-15-9)
- Adamantan-1-yl(phenyl)methanamine (CAS 139026-44-1)
- 5-(Adamantan-1-yl)-2-methylaniline (CAS 26378-31-4)
- 1-n-(Adamantan-1-yl)benzene-1,2-diamine (CAS 160917-93-1)
- 2-(Adamantan-1-ylthio)propanoic acid (CAS 96196-77-9)
- Adamantan-1-yl-phenyl-methanone (CAS 31919-47-8)
- 2-(Adamantan-1-yl)ethane-1-sulfonamide (CAS 1283719-69-6)
- 1-(Adamantan-1-yl)-3-ethylthiourea (CAS 25444-84-2)
Recommended Standards
- Threohydroxy Bupropion (CAS 92264-82-9)
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- 3-(4-Chlorophenoxy)-N,N-diethylpropan-1-amine (CAS 415722-40-6)
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- 2-Methyl-4-phenyl-1-(prop-2-yn-1-yl)-1H-imidazol-5-amine (CAS 1247424-61-8)
- 2-[3,5-Dibromo-4-(propan-2-yloxy)phenyl]-1,3-dioxolane (CAS 2221812-17-3)
- 2H-chromene-8-carboxylic acid (CAS 1935147-76-4)
- 2-Chloro-n-{4-[(3,5-dimethylpiperidin-1-yl)sulfonyl]phenyl}acetamide (CAS 908509-71-7)
- Ethyl 2-amino-4-(3,4-dichlorophenyl)-6-(hydroxymethyl)-8-oxo-4H,8H-pyrano[3,2-b]pyran-3-carboxylate (CAS 664999-77-3)
- Spashentan Impurity 3 (CAS 2567159-90-2)
- 2,4-Dichloro-6-(pyren-1-yl)-1,3,5-triazine (CAS 3224-36-0)
- 1-Bromo-2,4-dichloro-5-(trifluoromethoxy)benzene (CAS 1255574-72-1)
- Fibrinopeptide B (human) (CAS 36204-23-6)
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