Polymyxin B1-I CAS 811435-10-6
| CAS No. | 811435-10-6 |
| Molecular Formula | C56H98N16O13 |
| Molecular Weight | 1203.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Polymyxin B1-I (CAS 811435-10-6), a certified reference material (molecular formula C56H98N16O13, MW 1203.48 g/mol) for analytical method development and quality control.
The molecular framework of Polymyxin B1-I (C56H98N16O13) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Polymyxin B1-I meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C56H98N16O13 |
| Molecular Weight | 1203.48 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 16 |
Related Polymyxin Standards
- Polymyxin B1 (CAS 4135-11-9)
- Polymyxin Impurity 22 (CAS CATO-C4X-225522)
- Polymyxin Impurity 23 (CAS CATO-C4X-225523)
- Polymyxin Impurity 32 (CAS CATO-C4X-225532)
- Polymyxin Impurity 31 (CAS CATO-C4X-225531)
- Polymyxin B3 (CAS 71140-58-4)
- Polymyxin B2 (CAS 34503-87-2)
- Polymyxin Impurity 25 (CAS CATO-C4X-225525)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com