methyl 4-chloropyrimidine-2-carboxylate CAS 811450-17-6
| CAS No. | 811450-17-6 |
| Molecular Formula | C6H11ClN2O2 |
| Molecular Weight | 178.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
methyl 4-chloropyrimidine-2-carboxylate (CAS 811450-17-6) is a high-purity analytical reference standard with the molecular formula C6H11ClN2O2 and a molecular weight of 178.62 g/mol.
methyl 4-chloropyrimidine-2-carboxylate (C6H11ClN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures methyl 4-chloropyrimidine-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H11ClN2O2 |
| Molecular Weight | 178.62 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related methyl Standards
- methyl 2-chloropyrimidine-5-carboxylate (CAS 287714-35-6)
- 2-Chloropyrimidine-5-carbonyl chloride (CAS 110099-99-5)
- 4-Chloropyrimidine-5-carbonyl chloride (CAS 1261494-35-2)
- 2-Chloropyrimidine-4-carbonyl chloride (CAS 149849-93-4)
- 6-Chloropyrimidine-4-carbonyl chloride (CAS 263270-52-6)
- Methyl 4-Chloropyrimidine-5-carboxylate (CAS 1246471-45-3)
- Methyl 5-chloropyrimidine-4-carboxylate (CAS 124999-47-9)
- Methyl 2-chloropyrimidine-4-carboxylate (CAS 149849-94-5)
Recommended Standards
- Methyl 5-Chloro-2-pyrazinecarboxylate (CAS 33332-25-1)
- Bromisoval Impurity 4 (CAS 61345-66-2)
- methyl 6-chloropyridazine-3-carboxylate (CAS 65202-50-8)
- 8-Chloroquinolin-6-amine (CAS 50358-62-8)
- 4-(1,3-Dioxaindan-5-ylmethylidene)-2-tert-butyl-1,2,3,4-tetrahydroacridine-9-carboxylic acid (CAS 647036-25-7)
- N2-Methylpyridine-2,4-diamine (CAS 920520-39-4)
- 2-Bromo 17-beta-Estradiol (CAS 15833-07-5)
- 4-Methoxy-3-oxobutanenitrile (CAS 739366-02-0)
- 2-(2-Aminoethanesulfonyl)-2-methylpropane hydrochloride (CAS 947664-96-2)
- Pyridostigmine Impurity 4 (CAS CATO-C4X-26304)
- 2-Chloro-N-ethylbenzamide (CAS 66896-65-9)
- Ethyl 3-Acetamido-4-hydroxybenzoate (CAS 164408-49-5)
- (5-(Aminomethyl)thiophen-2-yl)(thiophen-2-yl)methanol (CAS 1447967-18-1)
- Semaglutide impurity 96 (CAS CATO-C4X-222696)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com