4-Amino-N-(3-(trifluoromethyl)phenyl)benzamide CAS 811841-49-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Amino-N-(3-(trifluoromethyl)phenyl)benzamide.

4-Amino-N-(3-(trifluoromethyl)phenyl)benzamide (CAS 811841-49-3) is a high-purity analytical reference standard with the molecular formula C14H11F3N2O and a molecular weight of 280.25 g/mol.

The molecular framework of 4-Amino-N-(3-(trifluoromethyl)phenyl)benzamide (C14H11F3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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