3-Isobutyl-3,4,7,12-tetrahydro-1H-[1,2,5]triazepino[1,2-b]phthalazine-1,5(2H)-dione CAS 81215-71-6
| CAS No. | 81215-71-6 |
| Molecular Formula | C16H21N3O2 |
| Molecular Weight | 287.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-Isobutyl-3,4,7,12-tetrahydro-1H-[1,2,5]triazepino[1,2-b]phthalazine-1,5(2H)-dione (CAS 81215-71-6), molecular formula C16H21N3O2 and molecular weight 287.36 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Isobutyl-3,4,7,12-tetrahydro-1H-[1,2,5]triazepino[1,2-b]phthalazine-1,5(2H)-dione (C16H21N3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 3-Isobutyl-3,4,7,12-tetrahydro-1H-[1,2,5]triazepino[1,2-b]phthalazine-1,5(2H)-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H21N3O2 |
| Molecular Weight | 287.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Nitrogen Atoms | 3 |
Related Isobutyl Standards
- 2-Isobutyl-2-(2-(trifluoromethoxy)phenyl)pyrrolidine (CAS 1513405-40-7)
- N-(5-Isobutyl-1,3,4-thiadiazol-2-yl)-3,4-dimethylbenzamide (CAS 510735-82-7)
- 2-Isobutyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile (CAS 856167-68-5)
- N-Isobutyl-2-methyl-4-(pyrrolidin-1-yl)quinazolin-7-amine (CAS 646450-80-8)
- 2-Isobutyl-1-oxo-2,9-dihydro-1H-pyrido[3,4-b]indole-4-carboxylic acid (CAS 1023517-03-4)
- 2-[(5-Isobutyl-2-isopropyl-1-piperazinyl)methyl]phenol (CAS 1353497-72-9)
- N-isobutyl-N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine (CAS 1015242-06-4)
- Methyl 3-isobutyl-2-mercapto-4-oxo-3,4-dihydroquinazoline-7-carboxylate (CAS 855715-37-6)
Recommended Standards
- 3-Benzyl-7-methylhexahydro-1H-pyridazino[1,2-a][1,2,5]triazepine-1,5(2H)-dione (CAS 67744-73-4)
- 3-Tosylthiazolidine-2-carboxylic acid (CAS 408360-05-4)
- 3-(Thiomorpholinosulfonyl)benzoic acid (CAS 799262-54-7)
- 4-(1-Pyrenyl)butyramide (CAS 71942-36-4)
- 5-Bromo-2-chloro-3-(difluoromethoxy)pyridine (CAS 1211533-38-8)
- tert-Butyl (S)-2-(4-(4-fluorobenzoyl)thiazol-2-yl)pyrrolidine-1-carboxylate (CAS 1005342-78-8)
- 6-Acetyl-7-[(E)-2-(dimethylamino)ethenyl]pyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 130506-87-5)
- Landiolol Impurity 118 (CAS CATO-C4X-2621118)
- 5-(P-tolyl)isoxazole-4-carboxylic acid (CAS 887408-19-7)
- 3-(quinolin-4-yl)prop-2-enoic acid (CAS 13026-20-5)
- Ammonium 2-(tert-butoxycarbonyl)benzoate (CAS 101976-13-0)
- 2,6-Dimethyl-9H-fluoren-9-one (CAS 21436-48-6)
- (2R,3S,4R,5S,6S)-2-(2-azidoethoxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol (CAS 153252-86-9)
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com