1-(1H-indol-6-yl)ethanone CAS 81223-73-6
| CAS No. | 81223-73-6 |
| Molecular Formula | C10H17NO |
| Molecular Weight | 167.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(1H-indol-6-yl)ethanone is closely related to an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(1H-indol-6-yl)ethanone (CAS 81223-73-6), molecular formula C10H17NO and molecular weight 167.25 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(1H-indol-6-yl)ethanone (C10H17NO) is characterized by an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H17NO |
| Molecular Weight | 167.25 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1980 |
| Nitrogen Atoms | 1 |
Related H Standards
- 2-(Indol-3-yl)ethylisocyanide (CAS 100571-64-0)
- 3-(1H-Indol-7-yl)propanenitrile (CAS 140639-84-5)
- 2-(1H-Indol-3-yl)propanenitrile (CAS 20862-85-5)
- 3-(1H-indol-3-yl)propanenitrile (CAS 4414-76-0)
- 1-(1h-Indol-3-yl)prop-2-en-1-one (CAS 77221-81-9)
- 3-(1h-Indol-3-yl)acrylaldehyde (CAS 923293-03-2)
- (1H-indol-3-yl)methanethiol (CAS 86204-60-6)
- 2-((1H-Indol-4-yl)oxy)acetonitrile (CAS 118855-76-8)
Recommended Standards
- 1-(1h-Imidazol-1-yl)-3,3-dimethylbutan-2-amine (CAS 845290-87-1)
- 1-(2,2-Dimethylpropyl)-5-methyl-1h-pyrazol-4-amine (CAS 725746-88-3)
- 1-(1-Ethyl-3,5-dimethyl-1h-pyrazol-4-yl)ethan-1-amine (CAS 936940-41-9)
- 1-(3-Isopropyl-5-methyl-3,4-dihydro-2H-pyrrol-4-yl)ethanone (CAS 99188-66-6)
- 1,5-Naphthyridine-2,6-diamine (CAS 42309-17-1)
- 5-Bromo-N-(4-methoxy-2-nitrophenyl)pyrazin-2-amine (CAS 950845-94-0)
- tert-Butyl 7-(2-hydroxyethyl)-2-methyl-6,7-dihydro-2H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate (CAS 1391732-47-0)
- Dapoxetine Impurity 8 (CAS CATO-C4X-14398)
- tert-Butyl 3-(((5-nitropyridin-2-yl)thio)methyl)piperidine-1-carboxylate (CAS 1353958-98-1)
- 2-Acetyl-3-chloroisoquinolin-1(2H)-one (CAS 110513-68-3)
- 1-(2-(2-Chloroethoxy)ethyl)-1h-1,2,4-triazole (CAS 108223-79-6)
- Ethyl 5-bromo-4-(trifluoromethyl)thiazole-2-carboxylate (CAS 1086393-21-6)
- Stiripentol impurity 1 (CAS CATO-C4X-32291)
- Semaglutide impurity 98 (CAS CATO-C4X-222698)
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