5-Acetyl-1-(morpholinomethyl)-3,3-diphenylindolin-2-one CAS 81252-98-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Acetyl-1-(morpholinomethyl)-3,3-diphenylindolin-2-one.

5-Acetyl-1-(morpholinomethyl)-3,3-diphenylindolin-2-one (CAS 81252-98-4), molecular formula C27H26N2O3 and molecular weight 426.51 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 5-Acetyl-1-(morpholinomethyl)-3,3-diphenylindolin-2-one (C27H26N2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Acetyl-1-(morpholinomethyl)-3,3-diphenylindolin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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