3-Iodo-4-(prop-2-yn-1-yloxy)benzaldehyde CAS 812642-63-0
| CAS No. | 812642-63-0 |
| Molecular Formula | C10H7IO2 |
| Molecular Weight | 286.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Iodo-4-(prop-2-yn-1-yloxy)benzaldehyde.
3-Iodo-4-(prop-2-yn-1-yloxy)benzaldehyde (CAS 812642-63-0), molecular formula C10H7IO2 and molecular weight 286.07 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Iodo-4-(prop-2-yn-1-yloxy)benzaldehyde (C10H7IO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Iodo-4-(prop-2-yn-1-yloxy)benzaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7IO2 |
| Molecular Weight | 286.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | I-containing |
Related Iodo Standards
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- 1-(5-Iodo-2H-indazol-2-yl)ethan-1-one (CAS 1174064-60-8)
- 4-Iodo-3-methoxy-1,5-naphthyridine (CAS 1261365-88-1)
- 1-(6-Iodo-2H-indazol-2-yl)ethan-1-one (CAS 1305711-39-0)
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Recommended Standards
- 2-Cyano-N-(4-iodophenyl)acetamide (CAS 24522-29-0)
- 3-Iodo-6-methyl-4H-chromen-4-one (CAS 341528-94-7)
- 2-Cyano-N-(3-iodophenyl)acetamide (CAS 63034-92-4)
- 4,5-Dichloro-2-(4-nitrophenyl)-2,3-dihydropyridazin-3-one (CAS 24725-60-8)
- 1-(5-Chloro-2-nitrobenzoyl)pyrrolidine (CAS 541542-37-4)
- 4-Chloro-3-hydroxybenzoyl chloride (CAS 888731-75-7)
- 2-{[4-ethyl-5-(2-methylphenyl)-4h-1,2,4-triazol-3-yl]sulfanyl}acetic acid (CAS 741731-80-6)
- (3-Iodo-1-methyl-1H-indazol-5-yl)methanol (CAS 1422772-67-5)
- 2-(((3-Methylthiophen-2-yl)methyl)amino)acetic acid (CAS 656814-94-7)
- (E)-N'-(3-(2,4-dichlorophenyl)acryloyl)-4-methylbenzohydrazide (CAS 478041-74-6)
- 4-Chloro-2-(cyclohexylamino)benzonitrile (CAS 939816-39-4)
- 1,4-Dimethyl-3-(4-methylthiophen-3-yl)-1h-pyrazol-5-amine (CAS 1501500-01-1)
- Imrecoxib Impurity 8 (CAS CATO-C4X-23798)
- Q-Peptide trifluoroacetate salt (CAS 1361235-89-3)
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