Bisoprolol Impurity 69 CAS 81349-58-8

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.81349-58-8
Molecular FormulaC10H22O3
Molecular Weight190.28 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Bisoprolol Impurity 69 CAS 81349-58-8 chemical structure

Description

As a process- or degradation-related impurity, Bisoprolol Impurity 69 (CAS 81349-58-8, C10H22O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, Bisoprolol Impurity 69 is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 190.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Bisoprolol Impurity 69 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H22O3
Molecular Weight190.28 g/mol
Purity>95%
StorageStore at 2-8°C, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityHygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)0.0
CAS Registry Year (est.)1980

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