Methyl 1-Boc-4-oxopiperidine-2-carboxylate CAS 81357-18-8
| CAS No. | 81357-18-8 |
| Molecular Formula | C12H19NO5 |
| Molecular Weight | 257.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 257.28 g/mol gives Methyl 1-Boc-4-oxopiperidine-2-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 1-Boc-4-oxopiperidine-2-carboxylate (CAS 81357-18-8), molecular formula C12H19NO5 and molecular weight 257.28 g/mol, is a CATO reference standard with documented purity and traceability.
Methyl 1-Boc-4-oxopiperidine-2-carboxylate (C12H19NO5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Methyl 1-Boc-4-oxopiperidine-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H19NO5 |
| Molecular Weight | 257.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Nitrogen Atoms | 1 |
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Why CATO?
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