Alfuzosin EP Impurity D hydrochloride CAS 81403-69-2
| CAS No. | 81403-69-2 |
| Molecular Formula | C14H21N5O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Alfuzosin EP Impurity D hydrochloride (CAS 81403-69-2, C14H21N5O2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C14H21N5O2HCl, Alfuzosin EP Impurity D hydrochloride contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 327.81 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C14H21N5O2 HCl |
| Molecular Weight | 327.81 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Alfuzosin Standards
- Alfuzosin-d (CAS 1006717-24-3)
- Alfuzosin-D6 (CAS 1006717-31-2)
- Alfuzosin EP Impurity E (CAS 1026411-59-5)
- Alfuzosin-d3 Hydrochloride (CAS 1216383-97-9)
- (±)-Alfuzosin D7 Hydrochloride (CAS 1276197-14-8)
- Alfuzosin EP Impurity B Hydrochloride (CAS 132900-51-7)
- Alfuzosin-d7 (CAS 1346746-88-0)
- Alfuzosin EP Impurity E HCl (CAS 1796934-51-4)
Recommended Standards
- Baloxavir Marboxil Impurity 200 (CAS CATO-C4X-2108200)
- Cefamandole Impurity 24 (CAS CATO-C4X-122124)
- Folic Acid Impurity 63 (CAS CATO-C4X-139563)
- N-(4-(Hydroxymethyl)-2-iodophenyl)acetamide (CAS 1246250-02-1)
- 2-[3-(trifluoromethyl)-1H-pyrazol-1-yl]acetohydrazide (CAS 377767-16-3)
- N-(1-(1H-benzo[d]imidazol-2-yl)-3-methylbutyl)benzamide (CAS 25810-61-1)
- 4-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole (CAS 2803476-12-0)
- 4-(4-Chlorobenzyl)piperazine-2-carboxylic acid (CAS 1261229-75-7)
- 5H,6H,7H,8H,9H-pyrido[3,2-b]azepine (CAS 67203-48-9)
- Semaglutide Impurity 121 X Sodium Salt (CAS CATO-C4X-2226121)
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