(7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)-L-proline CAS 81432-12-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)-L-proline.

(7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)-L-proline (CAS 81432-12-4) is a high-purity analytical reference standard with the molecular formula C11H10N4O5 and a molecular weight of 278.22 g/mol.

(7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)-L-proline (C11H10N4O5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)-L-proline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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