2,6-Dimethylimidazo[1,2-a]pyridine-3-carboxylic acid CAS 81438-52-0
| CAS No. | 81438-52-0 |
| Molecular Formula | C10H10N2O2 |
| Molecular Weight | 190.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2,6-Dimethylimidazo[1,2-a]pyridine-3-carboxylic acid (CAS 81438-52-0), a certified reference material (molecular formula C10H10N2O2, MW 190.20 g/mol) for analytical method development and quality control.
The molecular framework of 2,6-Dimethylimidazo[1,2-a]pyridine-3-carboxylic acid (C10H10N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,6-Dimethylimidazo[1,2-a]pyridine-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10N2O2 |
| Molecular Weight | 190.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Nitrogen Atoms | 2 |
Related Dimethylimidazo Standards
- 5,7-Dimethylimidazo[1,2-a]pyridine-3-carboxylic acid (CAS 1159832-31-1)
- 2,4-Dimethylimidazo[1,5-a]pyrimidine-8-carboxamide (CAS 55418-16-1)
- 2,5-Dimethylimidazo[1,2-a]pyridine-3-carboxylic acid (CAS 81438-50-8)
- 5,7-Dimethylimidazo[1,2-a]pyridine-2-carboxylic acid (CAS 80353-95-3)
- (2,8-Dimethylimidazo[1,2-b]pyridazin-6-yl)boronic acid (CAS 2254505-85-4)
- n,7-Dimethylimidazo[1,2-a]pyridine-2-carboxamide (CAS 1223636-27-8)
- 1-(2,6-Dimethylimidazo[1,2-a]pyrazin-3-yl)ethanone (CAS 620604-03-7)
- 5,7-Dimethylimidazo[1,2-a]pyridine-2-carboxamide (CAS 70705-37-2)
Recommended Standards
- 2,6-Diaminopimelic acid (CAS 2577-62-0)
- 2-{imidazo[1,2-a]pyridin-2-yl}acetohydrazide (CAS 21755-37-3)
- 2,6-Diamino-5-methylquinazolin-4(1H)-one (CAS 56239-17-9)
- 2-Acetyl-5-methoxybenzofuran (CAS 21587-39-3)
- 2,2,2-Trifluoro-1-(1-(methylsulfonyl)-1H-indol-3-yl)ethan-1-one (CAS 342885-53-4)
- tert-Butyl (3-((((2,5-dioxopyrrolidin-1-yl)oxy)carbonyl)oxy)propyl)carbamate (CAS 613666-84-5)
- 4-Oxo-6-(trifluoromethyl)-4,5,6,7-tetrahydrobenzofuran-3-carboxylic acid (CAS 1420795-08-9)
- 1-((4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl)-2-(trityloxy)ethanone (CAS 681853-96-3)
- tert-Butyl 1,2,3,4,5,6-hexahydro-1,6-benzodiazocine-1-carboxylate (CAS 946386-51-2)
- 1-(2,5-Dimethylphenyl)-2,5-dimethyl-1h-pyrrole-3-carbaldehyde (CAS 872183-14-7)
- (2-(Difluoromethoxy)-6-methylphenyl)(pyridin-4-yl)methanone (CAS 1261468-28-3)
- Pramipexole Impurity 44 (CAS 1001648-65-2)
- CArbonic acid 3-fluoro-4-methyl-phenyl ester methyl ester (CAS 1936040-91-3)
- Liraglutide Impurity 25 (CAS CATO-C4X-199225)
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