N-[tert-Butyloxycarbonyl]-6-hydroxy-DL-norleucine CAS 81505-64-8
| CAS No. | 81505-64-8 |
| Molecular Formula | C11H21NO5 |
| Molecular Weight | 247.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-[tert-Butyloxycarbonyl]-6-hydroxy-DL-norleucine.
CATO supplies N-[tert-Butyloxycarbonyl]-6-hydroxy-DL-norleucine (CAS 81505-64-8), a certified reference material (molecular formula C11H21NO5, MW 247.29 g/mol) for analytical method development and quality control.
The molecular framework of N-[tert-Butyloxycarbonyl]-6-hydroxy-DL-norleucine (C11H21NO5) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-[tert-Butyloxycarbonyl]-6-hydroxy-DL-norleucine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H21NO5 |
| Molecular Weight | 247.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1980 |
| Nitrogen Atoms | 1 |
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