3-Benzyl-2-(methylthio)pyrimidin-4(3H)-one CAS 81560-08-9
| CAS No. | 81560-08-9 |
| Molecular Formula | C12H12N2OS |
| Molecular Weight | 232.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Benzyl-2-(methylthio)pyrimidin-4(3H)-one.
3-Benzyl-2-(methylthio)pyrimidin-4(3H)-one (CAS 81560-08-9) is a high-purity analytical reference standard with the molecular formula C12H12N2OS and a molecular weight of 232.30 g/mol.
The molecular framework of 3-Benzyl-2-(methylthio)pyrimidin-4(3H)-one (C12H12N2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Benzyl-2-(methylthio)pyrimidin-4(3H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H12N2OS |
| Molecular Weight | 232.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Benzyl Standards
- 6-benzyl-2-(methylthio)pyrimidin-4(3H)-one (CAS 100142-46-9)
- (4-(2-(Methylthio)pyrimidin-5-yl)phenyl)methanol (CAS 1349718-70-2)
- 1-Benzyl-2-(methylthio)-1H-imidazole-5-carbaldehyde (CAS 479400-30-1)
- 2-(Methylthio)-3-(m-tolyl)pyrimidin-4(3H)-one (CAS 89069-25-0)
- 2-(Methylthio)-5-(p-tolyl)pyrimidin-4(1H)-one (CAS 61044-91-5)
- 3-(2-(Methylthio)phenyl)-5,6-dihydro-4H-pyrrolo[3,2-d]isoxazole (CAS 603067-73-8)
- 3-(Methylthio)-[1,1'-biphenyl]-4,4'-diol (CAS 69432-61-7)
- 3-Methyl-2-(methylthio)-6-phenylpyrimidin-4(3H)-one (CAS 74303-68-7)
Recommended Standards
- 3-(Cinnamylthio)-1H-1,2,4-triazol-5-amine (CAS 861924-94-9)
- 3-Phenyl-5-(propan-2-ylidene)-2-thioxoimidazolidin-4-one (CAS 61632-47-1)
- 3-(Allylthio)-5-phenyl-4H-1,2,4-triazol-4-amine (CAS 341520-13-6)
- 4-((M-tolyloxy)methyl)thiophene-2-carbaldehyde (CAS 869947-75-1)
- 7-chloro-1-ethyl-1H-1,3-benzodiazole-2-carbaldehyde (CAS 1343356-00-2)
- 3,6-Bis(trifluoromethyl)benzene-1,2-diamine (CAS 106877-22-9)
- tert-Butyl 2-bromo-4-methylthiazole-5-carboxylate (CAS 81569-41-7)
- 2-Amino-5-bromobenzamide (CAS 16313-66-9)
- 2-Iodo-5-methylpyrazine (CAS 914452-70-3)
- (R)-1-(3-Phenyl-3H-imidazo[4,5-b]pyridin-2-yl)ethanamine (CAS 1398507-85-1)
- 5-(3,5-Bis(trifluoromethyl)phenyl)furan-2-carbonitrile (CAS 2197056-54-3)
- 2,5-Dichloro-N-morpholinobenzenesulfonamide (CAS 294849-19-7)
- 1,1,3-Trichlorotrifluoroacetone (CAS 79-52-7)
- 30003-72-6 insulin chain b oxidized (CAS 30003-72-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com