5-Bromo-4-methylthiophene-2-sulfonyl chloride CAS 81597-51-5

Purity 97%+In StockPharmaceutical Standards
CAS No.81597-51-5
Molecular FormulaC5H4BrClO2S2
Molecular Weight275.57 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Bromo-4-methylthiophene-2-sulfonyl chloride CAS 81597-51-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 275.57 g/mol gives 5-Bromo-4-methylthiophene-2-sulfonyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 5-Bromo-4-methylthiophene-2-sulfonyl chloride (CAS 81597-51-5), a certified reference material (molecular formula C5H4BrClO2S2, MW 275.57 g/mol) for analytical method development and quality control.

Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, 5-Bromo-4-methylthiophene-2-sulfonyl chloride is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 275.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Bromo-4-methylthiophene-2-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC5H4BrClO2S2
Molecular Weight275.57 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1980
Halogen ContentCl/Br-containing
Sulfur Atoms2

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