Methyl 6-hydroxy-5-isopropyl-3-methylpyrazine-2-carboxylate CAS 816458-66-9
| CAS No. | 816458-66-9 |
| Molecular Formula | C10H14N2O3 |
| Molecular Weight | 210.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 6-hydroxy-5-isopropyl-3-methylpyrazine-2-carboxylate (CAS 816458-66-9) is a high-purity analytical reference standard with the molecular formula C10H14N2O3 and a molecular weight of 210.23 g/mol.
Methyl 6-hydroxy-5-isopropyl-3-methylpyrazine-2-carboxylate (C10H14N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 6-hydroxy-5-isopropyl-3-methylpyrazine-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14N2O3 |
| Molecular Weight | 210.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- Decamethylcyclopentasiloxane (CAS 541-02-6)
- 2-(3,4-Dihydronaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2361221-57-8)
- 1-(1-Isobutylcyclopropyl)-N-methylmethanamine (CAS 1543050-52-7)
- tert-butyl 6,9-diazaspiro[4.5]decane-6-carboxylate (CAS 886766-40-1)
- 3-Bromo-4-(phenylmethoxy)-benzonitrile (CAS 317358-76-2)
- Tirzepatide Impurity 51 (CAS CATO-C4X-324051)
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