(S)-(3-Hydroxy-2-methylpropyl)triphenylphosphonium bromide CAS 81658-46-0

Purity 97%+In StockPharmaceutical Standards
CAS No.81658-46-0
Molecular FormulaC22H24OP
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(S)-(3-Hydroxy-2-methylpropyl)triphenylphosphonium bromide CAS 81658-46-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 415.31 g/mol gives (S)-(3-Hydroxy-2-methylpropyl)triphenylphosphonium bromide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies (S)-(3-Hydroxy-2-methylpropyl)triphenylphosphonium bromide (CAS 81658-46-0), a certified reference material (molecular formula C22H24OPBr, MW 415.31 g/mol) for analytical method development and quality control.

The molecular framework of (S)-(3-Hydroxy-2-methylpropyl)triphenylphosphonium bromide (C22H24OPBr) is characterized by a steroid core, organophosphorus functionality, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures (S)-(3-Hydroxy-2-methylpropyl)triphenylphosphonium bromide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC22H24OP Br
Molecular Weight415.31 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1980
Halogen ContentBr-containing

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