tert-Butyl (2R,3S)-3-hydroxy-2-methylpyrrolidine-1-carboxylate CAS 817554-87-3

Description

Compared with other compounds in its class, the molecular weight of 201.26 g/mol gives tert-Butyl (2R,3S)-3-hydroxy-2-methylpyrrolidine-1-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

tert-Butyl (2R,3S)-3-hydroxy-2-methylpyrrolidine-1-carboxylate (CAS 817554-87-3), molecular formula C10H19NO3 and molecular weight 201.26 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of tert-Butyl (2R,3S)-3-hydroxy-2-methylpyrrolidine-1-carboxylate (C10H19NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), tert-Butyl (2R,3S)-3-hydroxy-2-methylpyrrolidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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