Glimepiride Impurity 23 CAS 81760-42-1
| CAS No. | 81760-42-1 |
| Molecular Formula | C8H12N2O2S |
| Molecular Weight | 200.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Glimepiride Impurity 23 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Glimepiride Impurity 23 (CAS 81760-42-1), a pharmacopoeial impurity reference standard (molecular formula C8H12N2O2S, MW 200.26 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Glimepiride Impurity 23 (C8H12N2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C8H12N2O2S |
| Molecular Weight | 200.26 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Glimepiride Standards
- Glimepiride Impurity 24 (CAS 138428-37-2)
- Glimepiride Impurity 16 (CAS 247098-17-5)
- Glimepiride Impurity 20 (CAS 607-97-6)
- Glimepiride Impurity 18 (CAS 41176-69-6)
- Glimepiride Impurity 25 (CAS CATO-C4X-110225)
- Glimepiride Impurity 14 (CAS 1943-82-4)
- Glimepiride Impurity 14 (CAS 38258-74-1)
- Glimepiride Impurity 21 (CAS 32175-00-1)
Recommended Standards
- 3-(1-(ethylsulfonyl)azetidin-3-yl)acrylonitrile (CAS CATO-C3D-262664)
- Duloxetine Impurity 23 (CAS CATO-C4X-133623)
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- Duloxetine Impurity 37 (CAS CATO-C4X-133637)
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- Octreotide Impurity 30 (CAS CATO-C4X-152030)
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- N-Boc-N-methyl-DL-alanine (CAS 13734-31-1)
- 3-[4-(4-Biphenylylamino)phenyl]-9-phenylcarbazole (CAS 1160294-96-1)
- (S)-Benzyl 3-(ethyl(2-hydroxyethyl)amino)pyrrolidine-1-carboxylate (CAS 1354019-64-9)
- Aniline D5 (CAS 4165-61-1)
- Palmitoyl Hexapeptide-12 TFA salt (CAS 171263-26-6(Free Base))
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