Loxoprofen Impurity 5 CAS 81762-82-5
| CAS No. | 81762-82-5 |
| Molecular Formula | C17H22O3 |
| Molecular Weight | 274.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Loxoprofen Impurity 5 is closely related to a steroid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Loxoprofen Impurity 5 (CAS 81762-82-5), a pharmacopoeial impurity reference standard (molecular formula C17H22O3, MW 274.35 g/mol) used for the identification and quantification of trace impurities in APIs.
Loxoprofen Impurity 5 (C17H22O3) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Loxoprofen Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H22O3 |
| Molecular Weight | 274.35 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
Related Loxoprofen Standards
- Loxoprofen Impurity 159 (CAS CATO-C4X-1488159)
- Loxoprofen Impurity 33 (CAS 98986-08-4)
- Loxoprofen Impurity 3 (CAS 1091621-61-2)
- Loxoprofen Impurity 32 (CAS 2514697-36-8)
- Loxoprofen Impurity 4 (CAS CATO-C4X-14884)
- Loxoprofen Impurity 88 (CAS 1616730-60-9)
- Loxoprofen Impurity 149 (CAS CATO-C4X-1488149)
- Loxoprofen Impurity 56 (CAS 200554-09-2)
Recommended Standards
- 898754-66-0 1-(3-Fluorophenyl)-3-[2-(methylsulfanyl)phenyl]propan-1-one DTXSID60644323 (CAS 898754-66-0)
- Cyclandelate Impurity 1 (CAS 16623-22-6)
- (1S,4aS)-7-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid 61597-83-9 ST24033663 (CAS 61597-83-9)
- Nilestriol Impurity 4 (CAS CATO-C4X-24514)
- Urapidil Impurity 24 (CAS CATO-C4X-192424)
- Deoxycholic acid Impurity 29 (CAS 61289-17-6)
- Ketorolac Impurity 79 (CAS CATO-C4X-166979)
- (R)-N-(2,5-Dioxotetrahydrofuran-3-yl)-2-phenoxyacetamide (CAS 1245647-39-5)
- 3-((1S,2S,3S)-2,3-Dimethyl-2-(((2-oxo-2H-chromen-7-yl)oxy)methyl)-6-(propan-2-ylidene)cyclohexyl)propanoic acid (CAS 3566-55-0)
- 2,4-Dibromo-1,5-difluoro-3-nitrobenzene (CAS 144450-58-8)
- Dexpanthenol Impurity 21 Sodium Salt (CAS 1112-32-9 (free acid))
- 2,3-Dimethyl-3-(2-thiomethylphenyl)propiophenone (CAS 898754-72-8)
- 2-(4-Fluorophenyl)-1h-1,3-benzodiazole-6-carboxylic acid (CAS 850705-30-5)
- (His32,Leu34)-Neuropeptide Y (32-36) (CAS 168916-68-5)
Why CATO?
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