1-Methyl-5-(trifluoromethyl)-1H-imidazole CAS 81769-70-2
| CAS No. | 81769-70-2 |
| Molecular Formula | C5H5F3N2 |
| Molecular Weight | 150.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-Methyl-5-(trifluoromethyl)-1H-imidazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 1-Methyl-5-(trifluoromethyl)-1H-imidazole (CAS 81769-70-2), a certified reference material (molecular formula C5H5F3N2, MW 150.10 g/mol) for analytical method development and quality control.
The molecular framework of 1-Methyl-5-(trifluoromethyl)-1H-imidazole (C5H5F3N2) is characterized by a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H5F3N2 |
| Molecular Weight | 150.10 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- 3-Methyl-5-(trifluoromethyl)pyrazole (CAS 10010-93-2)
- 4-Methyl-3-(trifluoromethyl)-1h-pyrazole (CAS 153085-14-4)
- 1-Methyl-5-(trifluoromethyl)pyrazole (CAS 153085-15-5)
- 1-Methyl-3-(trifluoromethyl)-1H-pyrazole (CAS 154471-65-5)
- 1-Methyl-4-(trifluoromethyl)-1H-pyrazole (CAS 176214-16-7)
- 1-Methyl-4-(trifluoromethyl)-1H-imidazole (CAS 81769-69-9)
- 2-Methyl-4-(trifluoromethyl)furan (CAS 26431-54-9)
- 2-Methyl-4-(trifluoromethyl)imidazole (CAS 33468-67-6)
Recommended Standards
- 1-(2,2,2-Trifluoroethyl)-1h-imidazole (CAS 91461-55-1)
- 3-(2,2,2-Trifluoroethyl)-1H-pyrazole (CAS 1946822-36-1)
- 3-Methyl-4-(trifluoromethyl)-1H-pyrazole (CAS 864239-61-2)
- 5-Methyl-3-(trifluoromethyl)-1H-pyrazole (CAS 942060-04-0)
- (E)-[(4-Methylphenyl)methylidene]({2-[(E)-[(4-methylphenyl)methylidene]amino]ethyl})amine (CAS 552859-12-8)
- 4-Bromo-2,3-difluoropyridine (CAS 1227597-53-6)
- (3-Amino-6-methyl-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl)(4-fluorophenyl)methanone (CAS 354556-60-8)
- 1-(8-(tert-Butoxycarbonyl)-1-oxa-2,8-diazaspiro[4.5]dec-2-en-3-yl)piperidine-4-carboxylic acid (CAS 1251003-31-2)
- 1-Bromo-2,2-dimethylhexane (CAS 101419-70-9)
- (S)-4-(tert-butoxycarbonyl)-1-methylpiperazine-2-carboxylic acid (CAS 2165707-14-0)
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- Dimefline Impurity 10 (CAS 95279-60-0)
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