2-(2,5-Dichlorobenzyl)-4,4-dimethylisoxazolidin-3-one CAS 81778-66-7

Purity 97%+In StockPharmaceutical Standards
CAS No.81778-66-7
Molecular FormulaC12H13Cl2NO2
Molecular Weight274.14 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(2,5-Dichlorobenzyl)-4,4-dimethylisoxazolidin-3-one CAS 81778-66-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 274.14 g/mol gives 2-(2,5-Dichlorobenzyl)-4,4-dimethylisoxazolidin-3-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-(2,5-Dichlorobenzyl)-4,4-dimethylisoxazolidin-3-one (CAS 81778-66-7), molecular formula C12H13Cl2NO2 and molecular weight 274.14 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2-(2,5-Dichlorobenzyl)-4,4-dimethylisoxazolidin-3-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 274.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-(2,5-Dichlorobenzyl)-4,4-dimethylisoxazolidin-3-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H13Cl2NO2
Molecular Weight274.14 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1980
Halogen ContentCl-containing
Nitrogen Atoms1

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