Anthraquinone Impurity 2 CAS 82-21-3

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.82-21-3
Molecular FormulaC26H16O4
Molecular Weight392.40 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Anthraquinone Impurity 2 CAS 82-21-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 392.40 g/mol gives Anthraquinone Impurity 2 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Anthraquinone Impurity 2 (CAS 82-21-3), a pharmacopoeial impurity reference standard (molecular formula C26H16O4, MW 392.40 g/mol) used for the identification and quantification of trace impurities in APIs.

Anthraquinone Impurity 2 (C26H16O4) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC26H16O4
Molecular Weight392.40 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)19.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957

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