Loteprednol Etabonate CAS 82034-46-6
| CAS No. | 82034-46-6 |
| Molecular Formula | C24H31ClO7 |
| Molecular Weight | 466.95 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Loteprednol Etabonate.
Loteprednol Etabonate (CAS 82034-46-6), molecular formula C24H31ClO7 and molecular weight 466.95 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution, Loteprednol Etabonate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 466.95 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Loteprednol Etabonate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H31ClO7 |
| Molecular Weight | 466.95 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
Related Loteprednol Standards
- Loteprednol Etabonate 11-Oxo Impurity (CAS 207670-54-0)
- Loteprednol Impurity 5 (CAS CATO-C4X-19575)
- Loteprednol Impurity 7 (CAS CATO-C4X-19577)
- Loteprednol Impurity 6 (CAS CATO-C4X-19576)
- Loteprednol Impurity 15 (CAS CATO-C4X-195715)
- Loteprednol Impurity 4 (CAS 133991-62-5)
- Loteprednol impurity 14 (CAS 182068-96-8)
- Loteprednol Impurity 12 (CAS 133991-63-6)
Recommended Standards
- Sotagliflozin Impurity 1 (CAS CATO-C4X-30041)
- Lipoxamycin hemisulfate (CAS 11075-87-9)
- Empagliflozin impurity 192 (CAS CATO-C4X-1065192)
- 2-((5-(4-Chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-fluoro-4-methylphenyl)acetamide (CAS 477330-91-9)
- Methane-d1 (gas) (CAS 676-49-3)
- (1R,3r)-3-amino-1-methylcyclobutane-1-carboxylic acid (CAS 1389441-74-0)
- 2-Acetyl-3-fluoropyridine (CAS 87674-20-2)
- 4-{6-[(4-chlorophenyl)sulfanyl]-2-phenylpyrimidin-4-yl}morpholine (CAS 339019-31-7)
- methyl 4-ethyl-1,3-thiazole-5-carboxylate (CAS 114670-86-9)
- Ethyl 5-(5-methyl-2-pyridyl)-2-furoate (CAS 1187170-14-4)
- 2,4-Difluoro-6-nitroquinoline-3-carbonitrile (CAS 113944-50-6)
- 3'-(Hydroxymethyl)[1,1'-biphenyl]-4-carbonitrile (CAS 893739-15-6)
- 6-Ethynyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 627870-58-0)
- Tau Peptide (337-368) (Repeat 4 Domain) trifluoroacetate salt (CAS 330456-27-4)
Why CATO?
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