2,2,2-Trichloro-N-(pyridin-3-yl)acetamide CAS 82202-41-3
| CAS No. | 82202-41-3 |
| Molecular Formula | C7H5Cl3N2O |
| Molecular Weight | 239.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,2,2-Trichloro-N-(pyridin-3-yl)acetamide (C7H5Cl3N2O) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 2,2,2-Trichloro-N-(pyridin-3-yl)acetamide (CAS 82202-41-3), a certified reference material (molecular formula C7H5Cl3N2O, MW 239.49 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5Cl3N2O |
| Molecular Weight | 239.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Trichloro Standards
- 1-(2,3,5-Trichloro-6-hydroxyphenyl)ethan-1-one (CAS 101580-94-3)
- 2,3,5-Trichloro-4-methylbenzoic acid (CAS 89978-34-7)
- 2,4,6-Trichloro-3-methoxybenzaldehyde (CAS 704899-49-0)
- 1,3,5-Trichloro-2-isopropoxybenzene (CAS 116995-31-4)
- 2,4,6-Trichloro-3-ethyl-5-methylphenol (CAS 15460-04-5)
- 1,2,3-Trichloro-4-(propan-2-yloxy)benzene (CAS 1881289-14-0)
- 1,2,3-Trichloro-4-propoxybenzene (CAS 1881289-15-1)
- 1,3,5-Trichloro-2-propoxybenzene (CAS 1881322-19-5)
Recommended Standards
- (5-Chloro-6-(thiophen-3-yl)pyridin-3-yl)boronic acid (CAS 2225179-00-8)
- 2-Chloro-N-(3,5-dichloropyridin-2-yl)acetamide (CAS 735319-17-2)
- (5-Chloro-6-(thiophen-2-yl)pyridin-3-yl)boronic acid (CAS 2225155-08-6)
- Regorafenib Impurity 64 (CAS CATO-C4X-104764)
- Diethyl 2-(((5-chloropyridin-2-yl)amino)methylene)malonate (CAS 16867-57-5)
- Sorafenib related compound 26 (CAS 573673-43-5)
- 9052-45-3 2-Propenoic acid, polymer with diethenyl benzene 2-Propenoic acid, polymer with diethenylbenzene Acrylic acid, divinylbenzene polymer (CAS 9052-45-3)
- Rimegepant Impurity 63 (CAS 1071154-76-1)
- 5-Fluoro-2-methyl-2,3-dihydrobenzofuran-3-amine (CAS 1251258-92-0)
- 2,2'-(nitrosoazanediyl)diacetic acid (CAS 25081-31-6)
- 3-(4-Trifluoromethyl-pyridin-2-yl)-benzoic acid (CAS 1299607-69-4)
- 1-(PYRIDIN-2-YLCARBONYL)PIPERAZINE (CAS 39639-98-0)
- Methyl 3-bromo-5-hydroxy-2-methylbenzoate (CAS 2092700-79-1)
- Acetyl-Exenatide trifluoroacetate salt (CAS 305815-28-5)
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