Dimethyl (3,3-difluoro-2-oxo-3-phenylpropyl)phosphonate CAS 82302-97-4
| CAS No. | 82302-97-4 |
| Molecular Formula | C11H13F2O4P |
| Molecular Weight | 278.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dimethyl (3,3-difluoro-2-oxo-3-phenylpropyl)phosphonate.
Dimethyl (3,3-difluoro-2-oxo-3-phenylpropyl)phosphonate (CAS 82302-97-4), molecular formula C11H13F2O4P and molecular weight 278.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Dimethyl (3,3-difluoro-2-oxo-3-phenylpropyl)phosphonate (C11H13F2O4P) is characterized by a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Dimethyl (3,3-difluoro-2-oxo-3-phenylpropyl)phosphonate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H13F2O4P |
| Molecular Weight | 278.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | F-containing |
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