2-fluoro-4-hydroxy-Benzonitrile CAS 82380-18-5

Purity 97%+In StockPharmaceutical Standards
CAS No.82380-18-5
Molecular FormulaC7H4FNO
Molecular Weight137.11 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-fluoro-4-hydroxy-Benzonitrile CAS 82380-18-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 137.11 g/mol gives 2-fluoro-4-hydroxy-Benzonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-fluoro-4-hydroxy-Benzonitrile (CAS 82380-18-5), molecular formula C7H4FNO and molecular weight 137.11 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 2-fluoro-4-hydroxy-Benzonitrile is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 137.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H4FNO
Molecular Weight137.11 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1980
Halogen ContentF-containing
Nitrogen Atoms1

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