3-(4-Chlorophenyl)-1,2-thiazole-5-carboxylic acid CAS 82424-97-3
| CAS No. | 82424-97-3 |
| Molecular Formula | C10H6ClNO2S |
| Molecular Weight | 239.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(4-Chlorophenyl)-1,2-thiazole-5-carboxylic acid (CAS 82424-97-3) is a high-purity analytical reference standard with the molecular formula C10H6ClNO2S and a molecular weight of 239.68 g/mol.
Structurally, 3-(4-Chlorophenyl)-1,2-thiazole-5-carboxylic acid (C10H6ClNO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 239.68 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 3-(4-Chlorophenyl)-1,2-thiazole-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6ClNO2S |
| Molecular Weight | 239.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 2-(2-Chlorophenyl)-1,3-thiazole-5-carboxylic acid (CAS 1018520-26-7)
- 5-(2-Chlorophenyl)thiazole-4-carboxylic acid (CAS 1047676-25-4)
- 2-(4-Chlorophenyl)-4-hydroxy-6H-1,3-thiazin-6-one (CAS 1433-65-4)
- 2-(4-Chlorophenyl)thiazole-4-carboxylic Acid (CAS 17228-98-7)
- 2-(2-Chlorophenyl)-1,3-thiazole-4-carboxylic acid (CAS 944275-21-2)
- 2-(3-Chlorophenyl)-1,3-thiazole-4-carboxylic acid (CAS 845885-82-7)
- 2-(3-chlorophenyl)-1,3-thiazole-5-carboxylic acid (CAS 878555-97-6)
- 2-(4-Chlorophenyl)thiazole-5-carboxylic Acid (CAS 205692-14-4)
Recommended Standards
- 3-(3-Chlorophenyl)-1,2-thiazole-5-carboxylic acid (CAS 82424-96-2)
- 3-Chloro-5-phenylisothiazole-4-carboxylic acid (CAS 86125-06-6)
- 3-(2-chloro-1,3-benzothiazol-5-yl)prop-2-yn-1-yl acetate (CAS 2832329-60-7)
- 4-(3-Chlorophenyl)thiazole-2-carboxylic acid (CAS 886367-29-9)
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