2-piperidin-4-yl-1H-benzimidazole hydrochloride CAS 824403-74-9
| CAS No. | 824403-74-9 |
| Molecular Formula | C12H15N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-piperidin-4-yl-1H-benzimidazole hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-piperidin-4-yl-1H-benzimidazole hydrochloride (CAS 824403-74-9), molecular formula C12H15N3HCl and molecular weight 237.73 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 2-piperidin-4-yl-1H-benzimidazole hydrochloride is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 237.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H15N3 HCl |
| Molecular Weight | 237.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related piperidin Standards
- 1000339-76-3 Ethyl 2-(Piperidin-1-yl)-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate ethyl 2-(piperidin-1-yl)-4-trifluoromethyl-1,3-thiazole-5-carboxylate ethyl 2-piperidin-1-yl-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate (CAS 1000339-76-3)
- 2-(Piperidin-1-yl)-4-(trifluoromethyl)thiazole-5-carboxylic acid (CAS 1000339-77-4)
- Benzyl 2-(piperidin-4-yl)acetate hydrochloride (CAS 1000872-47-8)
- n-(Piperidin-3-ylmethyl)morpholine-4-carboxamide (CAS 1000941-33-2)
- 1000958-55-3 4-Ethyl-1-[2-(piperidin-4-yl)ethyl]piperidine DTXSID60649257 (CAS 1000958-55-3)
- 5-(Piperidin-2-yl)pyridin-2-amine (CAS 100133-12-8)
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- 1-methyl-5-(piperidin-1-ylcarbonyl)-1H-pyrazol-4-amine (CAS 1001500-82-8)
Recommended Standards
- (s)-2-piperidinone-6-carboxylic acid (s)-6-oxo-2-piperidinecarboxylic acid (s)-6-oxo-piperidine-2-carboxylic acid 34622-39-4 L-6-Oxo-pipecolinic acid (CAS 34622-39-4)
- 3-Chlorosulfonyl-4-methyl-benzoic acid methyl ester (CAS 372198-41-9)
- 4-(Fluoromethyl)piperidin-4-ol (CAS 1254031-75-8)
- (5-Methoxy-2-(methoxycarbonyl)pyridin-4-yl)boronic acid (CAS 2225174-46-7)
- (2-Chlorophenyl)(4,5-dimethyl-4H-1,2,4-triazol-3-yl)methanamine (CAS 1707610-29-4)
- 2-(1-Methoxynaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 627526-46-9)
- 5-Chloro-N-(2,2-dimethylthietan-3-yl)pyridin-2-amine (CAS 1870988-12-7)
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidine hydrochloride (CAS 1095545-12-2)
- 2-Methyl-3-(phenylsulfonyl)-1H-indole (CAS 107267-01-6)
- 141801-03-8 IL-1 Receptor Peptide (human) (CAS 141801-03-8)
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