2-Chloro-4,6-dimethoxybenzoic acid CAS 82477-60-9
| CAS No. | 82477-60-9 |
| Molecular Formula | C9H9ClO4 |
| Molecular Weight | 216.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 216.62 g/mol gives 2-Chloro-4,6-dimethoxybenzoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Chloro-4,6-dimethoxybenzoic acid (CAS 82477-60-9), molecular formula C9H9ClO4 and molecular weight 216.62 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Chloro-4,6-dimethoxybenzoic acid (C9H9ClO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H9ClO4 |
| Molecular Weight | 216.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
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Recommended Standards
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- 3-Azetidinomethyl-3,5-dimethylbenzophenone (CAS 898771-79-4)
- 2-(Chloromethyl)cyclohexanol (CAS 113662-55-8)
- Ethyl 7-fluoro-4-hydroxy-6-methoxyquinoline-3-carboxylate (CAS 851973-16-5)
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- Silmitasertib (CX-4945) Sodium Salt (CAS 1309357-15-0)
- 1-(5-chloro-4-nitro-pyrazol-1-yl)-2-methyl-propan-2-ol (CAS 1415099-67-0)
- Peptide 436 (CAS CATO-CPTD788436)
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