2’-Bromo-4’-chloroacetophenone CAS 825-40-1
| CAS No. | 825-40-1 |
| Molecular Formula | C8H6BrClO |
| Molecular Weight | 233.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 233.49 g/mol gives 2’-Bromo-4’-chloroacetophenone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2’-Bromo-4’-chloroacetophenone (CAS 825-40-1), molecular formula C8H6BrClO and molecular weight 233.49 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2’-Bromo-4’-chloroacetophenone (C8H6BrClO) is characterized by a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2’-Bromo-4’-chloroacetophenone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6BrClO |
| Molecular Weight | 233.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl/Br-containing |
Related Bromo Standards
- 5-Bromo-4-chloro-2-cyclopropylpyrimidine (CAS 1044767-90-9)
- 5’-Bromo-2’-chloroacetophenone (CAS 105884-19-3)
- 6-Bromo-2-Chloro-3-methylbenzaldehyde (CAS 1114808-98-8)
- 2-Bromo-6-chloro-3-methylbenzaldehyde (CAS 1114809-00-5)
- 121794-40-9 2-bromo-3-methylbenzyl acid chloride (CAS 121794-40-9)
- 4-Bromo-3-chloro-2-methylbenzaldehyde (CAS 1224604-13-0)
- 1-(2-Bromo-6-chlorophenyl)ethan-1-one (CAS 1261438-38-3)
- 7-Bromo-5-chloro-2,3-dihydrobenzofuran (CAS 134402-21-4)
Recommended Standards
- 2-(2-Bromophenyl)acetyl chloride (CAS 55116-09-1)
- 2’-Bromo-5’-chloroacetophenone (CAS 935-99-9)
- 2-(2-Bromo-5-chlorophenyl)acetaldehyde (CAS 265107-67-3)
- 2-Bromo-4-chloro-5-methylbenzaldehyde (CAS 2091146-62-0)
- (E)-Ethyl 3-(m-tolyloxy)acrylate (CAS 28991-07-3)
- 3-(3-Chloro-4,5-dimethoxyphenyl)-5-(chloromethyl)-1,2,4-oxadiazole (CAS 937630-31-4)
- 2,2-Dihydroxymalonic acid (CAS 560-27-0)
- (3S,4S)-1-benzyl-4-(methoxycarbonyl)pyrrolidine-3-carboxylic acid (CAS 111138-64-8)
- Montelukast Dehydro Impurity (CAS 168214-68-4)
- 2-(Sec-butoxy)-4-fluoroaniline (CAS 1042628-23-8)
- 3,5-Dichloro-1-(3,4-dimethylphenyl)pyrazin-2(1H)-one (CAS 1269530-87-1)
- N,N-dimethyl-4-((phenylamino)methyl)aniline (CAS 3526-44-1)
- 2-Oxo-3-(thiophen-2-yl)propanoic acid (CAS 15504-41-3)
- Insulin Degludec Impurity 8 (CAS CATO-C4X-21578)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com