2,4-Dichloro-5-cyanothiazole CAS 82554-18-5
| CAS No. | 82554-18-5 |
| Molecular Formula | C4Cl2N2S |
| Molecular Weight | 179.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2,4-Dichloro-5-cyanothiazole (CAS 82554-18-5), a certified reference material (molecular formula C4Cl2N2S, MW 179.03 g/mol) for analytical method development and quality control.
The molecular framework of 2,4-Dichloro-5-cyanothiazole (C4Cl2N2S) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4Cl2N2S |
| Molecular Weight | 179.03 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dichloro Standards
- 1,2-Dichloro-5-fluoro-3-methylbenzene (CAS 1242339-71-4)
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- 1,4-Dichloro-2-fluoro-5-methylbenzene (CAS 1365969-73-8)
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Recommended Standards
- 1,4-Oxaselenane-2,6-dione (CAS 30042-51-4)
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- 4,5-Dichlorothiazole-2-carbonitrile (CAS 62019-53-8)
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- PNU 74654 (CAS 113906-27-7)
- (S)-1-Neopentylpyrrolidin-3-amine (CAS 1286207-45-1)
- Methyl 4-cyclopentyl-3-oxo-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine-7-carboxylate (CAS 1708179-13-8)
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- Lixisenatide (CAS 320367-13-3)
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