5,8-Difluoro-2-methylquinazolin-4(3H)-one CAS 825654-55-5
| CAS No. | 825654-55-5 |
| Molecular Formula | C9H6F2N2O |
| Molecular Weight | 196.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 196.15 g/mol gives 5,8-Difluoro-2-methylquinazolin-4(3H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5,8-Difluoro-2-methylquinazolin-4(3H)-one (CAS 825654-55-5) is a high-purity analytical reference standard with the molecular formula C9H6F2N2O and a molecular weight of 196.15 g/mol.
The molecular framework of 5,8-Difluoro-2-methylquinazolin-4(3H)-one (C9H6F2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5,8-Difluoro-2-methylquinazolin-4(3H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H6F2N2O |
| Molecular Weight | 196.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoro Standards
- 6,7-Difluoro-2-methylquinazolin-4(3H)-one (CAS 1033778-42-5)
- 3,4-Difluoro-benzenesulfonyl fluoride (CAS 115561-01-8)
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Recommended Standards
- 5-(3,5-Difluorophenyl)oxazol-2-amine (CAS 933752-57-9)
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- 2-(6-Amino-5-bromo-4-(difluoromethyl)pyridin-3-yl)acetic acid (CAS 1805092-32-3)
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- Methyl 2-ethoxy-6-methyl-3,4,5,6-tetrahydropyridine-3-carboxylate (CAS 1710846-07-3)
- N-Hydroxy-2-[methyl(tetrahydro-2H-pyran-4-ylmethyl)amino]benzenecarboximidamide (CAS 1220040-43-6)
- 1-(Morpholin-4-yl)-3-phenylpropan-2-amine (CAS 1021146-87-1)
- Di-tert-butyl2,2'-((2-((2-aminoethyl)(dodecyl)amino)ethyl)azanediyl)diacetate (CAS 1610877-95-6)
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- Boc-trans-DL-β-pro-4-(4-pyridinyl)-OH (CAS 959579-54-5)
- N-[4-(sec-Butoxy)phenyl]-N-[2-(2-isopropyl-5-methylphenoxy)ethyl]amine (CAS 1040684-94-3)
- Insulin Glargine (CAS 160337-95-1)
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