N-(5-Methoxypyridin-2-yl)-N,2-dimethylquinazolin-4-amine CAS 827031-76-5

Purity 97%+In StockPharmaceutical Standards
CAS No.827031-76-5
Molecular FormulaC16H16N4O
Molecular Weight280.32 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(5-Methoxypyridin-2-yl)-N,2-dimethylquinazolin-4-amine CAS 827031-76-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 280.32 g/mol gives N-(5-Methoxypyridin-2-yl)-N,2-dimethylquinazolin-4-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies N-(5-Methoxypyridin-2-yl)-N,2-dimethylquinazolin-4-amine (CAS 827031-76-5), a certified reference material (molecular formula C16H16N4O, MW 280.32 g/mol) for analytical method development and quality control.

The molecular framework of N-(5-Methoxypyridin-2-yl)-N,2-dimethylquinazolin-4-amine (C16H16N4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC16H16N4O
Molecular Weight280.32 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Nitrogen Atoms4

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